טוען...

Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation

Identifying the forces that drive proteins to misfold and aggregate, rather than to fold into their functional states, is fundamental to our understanding of living systems and to our ability to combat protein deposition disorders such as Alzheimer's disease and the spongiform encephalopathies....

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מידע ביבליוגרפי
Main Authors: Fitzpatrick, Anthony W., Knowles, Tuomas P. J., Waudby, Christopher A., Vendruscolo, Michele, Dobson, Christopher M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192805/
https://ncbi.nlm.nih.gov/pubmed/22022239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002169
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