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A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation
The ability of many proteins to convert from their functional soluble state to amyloid fibrils can be attributed to inter-molecular beta strand formation. Such amyloid formation is associated with neurodegenerative disorders like Alzheimer's and Parkinson's. Molecular modelling can play a...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893179/ https://ncbi.nlm.nih.gov/pubmed/24454816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085185 |
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