FLIM-FRET imaging in vivo reveals 3D-environment spatially regulates RhoGTPase activity during cancer cell invasion

Many conceptual advances in biology have been achieved by experimental studies using planar two-dimensional cell culture systems. Recent adaptations of molecular techniques to three-dimensional model systems are bridging the gap in our understanding of biological events in vitro and in vivo in the s...

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Autori principali: McGhee, Ewan J, Morton, Jennifer P, Von Kriegsheim, Alex, Schwarz, Juliane P, Karim, Saadia A, Carragher, Neil O, Sansom, Owen J, Anderson, Kurt I, Timpson, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225915/
https://ncbi.nlm.nih.gov/pubmed/22145098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.4.17275
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