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Neonatal Fc receptor and IgG-based therapeutics

The majority of potent new biologics today are IgG-based molecules that have demonstrated tissue-targeting specificity with favorable clinical response. Several factors determine the efficacy of these products, including target specificity, serum half-life and effector functions via complement-depen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuo, Timothy T, Aveson, Victoria G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225846/
https://ncbi.nlm.nih.gov/pubmed/22048693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.5.16983
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