Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8(−)CD11b(+) dendritic cells

Cross-presentation of IgG-containing immune complexes (ICs) is an important means by which dendritic cells (DCs) activate CD8(+) T cells, yet it proceeds by an incompletely understood mechanism. We show that monocyte-derived CD8(−)CD11b(+) DCs require the neonatal Fc receptor for IgG (FcRn) to condu...

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Autori principali: Baker, Kristi, Qiao, Shuo-Wang, Kuo, Timothy T., Aveson, Victoria G., Platzer, Barbara, Andersen, Jan-Terje, Sandlie, Inger, Chen, Zhangguo, de Haar, Colin, Lencer, Wayne I., Fiebiger, Edda, Blumberg, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116387/
https://ncbi.nlm.nih.gov/pubmed/21628593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019037108
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