N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG

The neonatal Fc receptor (FcRn) is a major histocompatibility complex class I-related molecule known to protect IgG and albumin from catabolism and transport IgG across polarized epithelial cells in a bidirectional manner. Previous studies have shown species-specific differences in ligand binding, I...

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Autori principali: Kuo, Timothy T., de Muinck, Eric J., Claypool, Steven M., Yoshida, Masaru, Nagaishi, Takashi, Aveson, Victoria G., Lencer, Wayne I., Blumberg, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Membrane Transport, Structure, Function, and Biogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659187/
https://ncbi.nlm.nih.gov/pubmed/19164298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805877200
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