Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria

The neonatal Fc receptor for IgG (FcRn) plays a major role in regulating host IgG levels and transporting IgG and associated antigens across polarized epithelial barriers. Selective expression of FcRn in the epithelium is shown here to be associated with secretion of IgG into the lumen that allows f...

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Main Authors: Yoshida, Masaru, Kobayashi, Kanna, Kuo, Timothy T., Bry, Lynn, Glickman, Jonathan N., Claypool, Steven M., Kaser, Arthur, Nagaishi, Takashi, Higgins, Darren E., Mizoguchi, Emiko, Wakatsuki, Yoshio, Roopenian, Derry C., Mizoguchi, Atsushi, Lencer, Wayne I., Blumberg, Richard S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501111/
https://ncbi.nlm.nih.gov/pubmed/16841095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27821
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