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PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis
Mutations in the PARK6 gene coding for PTEN-induced kinase 1 (PINK1) cause recessive early-onset parkinsonism. Although PINK1 and Parkin promote the degradation of depolarized mitochondria in cultured cells, little is known about changes in signaling pathways that may additionally contribute to dopa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225697/ https://ncbi.nlm.nih.gov/pubmed/21945539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.08.034 |
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