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Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity

BACKGROUND: Exogenous insulin like growth factor-1 (IGF-1) is known to be neuroprotective in animal models with brain insults, while it can also cause hyperexcitability in rodents. In this regard, the role of endogenous IGF-1 in brain responses to brain insults like excitotoxicity, a common patholog...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Chen, Wei, He, Bin, Tong, Wusong, Zeng, Jinsong, Zheng, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629877/
https://ncbi.nlm.nih.gov/pubmed/31338023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00298
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