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Glutamine synthetase downregulation reduces astrocyte protection against glutamate excitotoxicity to neurons

Although the role of astrocyte glutamate transporters in glutamate clearance is well illustrated, the role of glutamine synthetase (GS) that influences this process remains to be elucidated. We examined whether GS affected the uptake of glutamate in astrocytes in vitro. The glutamate uptake was asse...

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Bibliografske podrobnosti
Main Authors: Zou, Jian, Wang, Yan-Xia, Dou, Fang-Fang, Lü, He-Zuo, Ma, Zheng-Wen, Lu, Pei-Hua, Xu, Xiao-Ming
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831119/
https://ncbi.nlm.nih.gov/pubmed/20064572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.12.021
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