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Glutamine synthetase downregulation reduces astrocyte protection against glutamate excitotoxicity to neurons

Although the role of astrocyte glutamate transporters in glutamate clearance is well illustrated, the role of glutamine synthetase (GS) that influences this process remains to be elucidated. We examined whether GS affected the uptake of glutamate in astrocytes in vitro. The glutamate uptake was asse...

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Hlavní autoři: Zou, Jian, Wang, Yan-Xia, Dou, Fang-Fang, Lü, He-Zuo, Ma, Zheng-Wen, Lu, Pei-Hua, Xu, Xiao-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831119/
https://ncbi.nlm.nih.gov/pubmed/20064572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.12.021
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