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Glutamine synthetase downregulation reduces astrocyte protection against glutamate excitotoxicity to neurons

Although the role of astrocyte glutamate transporters in glutamate clearance is well illustrated, the role of glutamine synthetase (GS) that influences this process remains to be elucidated. We examined whether GS affected the uptake of glutamate in astrocytes in vitro. The glutamate uptake was asse...

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Main Authors: Zou, Jian, Wang, Yan-Xia, Dou, Fang-Fang, Lü, He-Zuo, Ma, Zheng-Wen, Lu, Pei-Hua, Xu, Xiao-Ming
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831119/
https://ncbi.nlm.nih.gov/pubmed/20064572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.12.021
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