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Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation

BACKGROUND: Many neuroprotective approaches targeting neurons in animal models fail to provide benefits for the treatment of ischemic stroke in clinic and glial cells have become the targets in some basic studies. Baicalin has neuroprotective effects but the mechanisms related to glial cells are not...

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Bibliografski detalji
Izdano u:Redox Biol
Glavni autori: Song, Xianrui, Gong, Zixuan, Liu, Kaili, Kou, Junping, Liu, Baolin, Liu, Kang
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260594/
https://ncbi.nlm.nih.gov/pubmed/32473460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101559
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