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The Role of Glutamine Synthetase and Glutamate Dehydrogenase in Cerebral Ammonia Homeostasis
In the brain, glutamine synthetase (GS), which is located predominantly in astrocytes, is largely responsible for the removal of both blood-derived and metabolically generated ammonia. Thus, studies with [(13)N]ammonia have shown that about 25% of blood-derived ammonia is removed in a single pass th...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490058/ https://ncbi.nlm.nih.gov/pubmed/22618691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0803-4 |
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