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The Role of Glutamine Synthetase and Glutamate Dehydrogenase in Cerebral Ammonia Homeostasis

In the brain, glutamine synthetase (GS), which is located predominantly in astrocytes, is largely responsible for the removal of both blood-derived and metabolically generated ammonia. Thus, studies with [(13)N]ammonia have shown that about 25% of blood-derived ammonia is removed in a single pass th...

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Autor principal: Cooper, Arthur J. L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490058/
https://ncbi.nlm.nih.gov/pubmed/22618691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0803-4
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