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Glutamine synthetase downregulation reduces astrocyte protection against glutamate excitotoxicity to neurons
Although the role of astrocyte glutamate transporters in glutamate clearance is well illustrated, the role of glutamine synthetase (GS) that influences this process remains to be elucidated. We examined whether GS affected the uptake of glutamate in astrocytes in vitro. The glutamate uptake was asse...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831119/ https://ncbi.nlm.nih.gov/pubmed/20064572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.12.021 |
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