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Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones

ABSTRACT: Neuropeptide signalling at the plasma membrane is terminated by neuropeptide degradation by cell-surface peptidases, and by β-arrestin-dependent receptor desensitization and endocytosis. However, receptors continue to signal from endosomes by β-arrestin-dependent processes, and endosomal s...

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Bibliografische gegevens
Hoofdauteurs: Pelayo, Juan-Carlos, Poole, Daniel P, Steinhoff, Martin, Cottrell, Graeme S, Bunnett, Nigel W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225675/
https://ncbi.nlm.nih.gov/pubmed/21878523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.214452
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