Endosomal Endothelin-converting Enzyme-1: A REGULATOR OF β-ARRESTIN-DEPENDENT ERK SIGNALING

Neuropeptide signaling at the cell surface is regulated by metalloendopeptidases, which degrade peptides in the extracellular fluid, and β-arrestins, which interact with G protein-coupled receptors (GPCRs) to mediate desensitization. β-Arrestins also recruit GPCRs and mitogen-activated protein kinas...

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Detalhes bibliográficos
Main Authors: Cottrell, Graeme S., Padilla, Benjamin E., Amadesi, Silvia, Poole, Daniel P., Murphy, Jane E., Hardt, Markus, Roosterman, Dirk, Steinhoff, Martin, Bunnett, Nigel W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755963/
https://ncbi.nlm.nih.gov/pubmed/19531493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026674
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