Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and β-arrestins

Although cell surface metalloendopeptidases degrade neuropeptides in the extracellular fluid to terminate signaling, the function of peptidases in endosomes is unclear. We report that isoforms of endothelin-converting enzyme-1 (ECE-1a–d) are present in early endosomes, where they degrade neuropeptid...

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Detaylı Bibliyografya
Asıl Yazarlar: Padilla, Benjamin E., Cottrell, Graeme S., Roosterman, Dirk, Pikios, Stella, Muller, Laurent, Steinhoff, Martin, Bunnett, Nigel W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2007
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099187/
https://ncbi.nlm.nih.gov/pubmed/18039931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704053
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