Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2

BACKGROUND: Chronic hemodynamic overloading leads to heart failure (HF) due to incompletely understood mechanisms. To gain deeper insight into the molecular pathophysiology of volume overload-induced HF and to identify potential markers and targets for novel therapies, we performed proteomic and mRN...

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Hauptverfasser: Petrak, Jiri, Pospisilova, Jana, Sedinova, Miroslava, Jedelsky, Petr, Lorkova, Lucie, Vit, Ondrej, Kolar, Michal, Strnad, Hynek, Benes, Jan, Sedmera, David, Cervenka, Ludek, Melenovsky, Vojtech
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225319/
https://ncbi.nlm.nih.gov/pubmed/22078724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-9-69
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