Changes in Myocardial Composition and Conduction Properties in Rat Heart Failure Model Induced by Chronic Volume Overload

Volume overload leads to development of eccentric cardiac hypertrophy and heart failure. In our previous report, we have shown myocyte hypertrophy with no fibrosis and decrease in gap junctional coupling via connexin43 in a rat model of aorto-caval fistula at 21 weeks. Here we set to analyze the ele...

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Библиографические подробности
Главные авторы: David Sedmera, Jan Neckar, Jiri Benes, Jana Pospisilova, Jiri Petrak, Kamil Sedlacek, Vojtech Melenovsky
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016-08-01
Серии:Frontiers in Physiology
Предметы:
Hypertrophy
connexin43
conduction velocity
Aorto-caval fistula
autonomic heart innervation
Online-ссылка:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00367/full
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