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BCG sub-strains induce variable protection against virulent pulmonary Mycobacterium tuberculosis infection, with the capacity to drive Th2 immunity

The hallmark of a vaccine is to induce long-term protective immunity against the pathogen. The use of Mycobacterium bovis BCG as a vaccine against tuberculosis has been problematic in that immunity induced by BCG wanes over time and it may be less effective against more virulent strains of M. tuberc...

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Bibliografische gegevens
Hoofdauteurs: Keyser, Andrew, Troudt, JoLynn M., Taylor, Jennifer L., Izzo, Angelo A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225070/
https://ncbi.nlm.nih.gov/pubmed/22015391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.10.019
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