Kinetics of the Immune Response Profile in Guinea Pigs after Vaccination with Mycobacterium bovis BCG and Infection with Mycobacterium tuberculosis

The guinea pig model of tuberculosis is used extensively in assessing novel vaccines, since Mycobacterium bovis BCG vaccination effectively prolongs survival after low-dose aerosol infection with virulent M. tuberculosis. To better understand how BCG extends time to death after pulmonary infection w...

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Main Authors: Grover, Ajay, Taylor, Jennifer, Troudt, JoLynn, Keyser, Andrew, Arnett, Kimberly, Izzo, Linda, Rholl, Drew, Izzo, Angelo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772515/
https://ncbi.nlm.nih.gov/pubmed/19737892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00704-09
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