Identification of a Mycobacterium bovis BCG Auxotrophic Mutant That Protects Guinea Pigs against M. bovis and Hematogenous Spread of Mycobacterium tuberculosis without Sensitization to Tuberculin

Tuberculosis remains one of the most significant diseases of humans and animals. The only currently available vaccine against this disease is a live, attenuated vaccine, bacillus Calmette-Guérin (BCG), which was originally derived from Mycobacterium bovis and despite its variable efficacy is the mos...

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Main Authors: Chambers, Mark A., Williams, Ann, Gavier-Widén, Dolores, Whelan, Adam, Hall, Graham, Marsh, Philip D., Bloom, Barry R., Jacobs, William R., Hewinson, R. Glyn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97820/
https://ncbi.nlm.nih.gov/pubmed/11083835
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