Identification of a Mycobacterium bovis BCG Auxotrophic Mutant That Protects Guinea Pigs against M. bovis and Hematogenous Spread of Mycobacterium tuberculosis without Sensitization to Tuberculin

Tuberculosis remains one of the most significant diseases of humans and animals. The only currently available vaccine against this disease is a live, attenuated vaccine, bacillus Calmette-Guérin (BCG), which was originally derived from Mycobacterium bovis and despite its variable efficacy is the mos...

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Bibliographische Detailangaben
Hauptverfasser: Chambers, Mark A., Williams, Ann, Gavier-Widén, Dolores, Whelan, Adam, Hall, Graham, Marsh, Philip D., Bloom, Barry R., Jacobs, William R., Hewinson, R. Glyn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97820/
https://ncbi.nlm.nih.gov/pubmed/11083835
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