Identification of a Mycobacterium bovis BCG Auxotrophic Mutant That Protects Guinea Pigs against M. bovis and Hematogenous Spread of Mycobacterium tuberculosis without Sensitization to Tuberculin

Tuberculosis remains one of the most significant diseases of humans and animals. The only currently available vaccine against this disease is a live, attenuated vaccine, bacillus Calmette-Guérin (BCG), which was originally derived from Mycobacterium bovis and despite its variable efficacy is the mos...

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Pubblicato in:	Infect Immun
Autori principali:	Chambers, Mark A., Williams, Ann, Gavier-Widén, Dolores, Whelan, Adam, Hall, Graham, Marsh, Philip D., Bloom, Barry R., Jacobs, William R., Hewinson, R. Glyn
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Host Response and Inflammation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083835/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.12.7094-7099.2000
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