Mycobacterium tuberculosis sigE mutant ST28 used as a vaccine induces protective immunity in the guinea pig model

With more than 9 million new infections and 1.5 million deaths claimed every year, tuberculosis remains one of the major scourges of humankind. The only vaccine available against this disease, the attenuated strain Mycobacterium bovis, BCG is effective against severe forms of the disease in infants,...

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Bibliographische Detailangaben
Veröffentlicht in:Tuberculosis (Edinb)
Hauptverfasser: Troudt, JoLynn, Creissen, Elizabeth, Izzo, Linda, Bielefeldt-Ohmann, Helle, Casonato, Stefano, Manganelli, Riccardo, Izzo, Angelo A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570617/
https://ncbi.nlm.nih.gov/pubmed/28802412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2017.07.009
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