Evaluation of Peripheral Blood Markers as Early Endpoint Criteria in Guinea Pigs (Cavia porcellus) when Testing Tuberculosis Vaccine Candidates

The guinea pig model of tuberculosis is used extensively to assess the efficacy of novel tuberculosis vaccines. There are established parameters to determine vaccine efficacy in this model, but the science community currently lacks established biomarkers for early detection and monitoring of experim...

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Detalhes bibliográficos
Publicado no:Comp Med
Main Authors: Williams, Wendy R, Troudt, JoLynn, Creissen, Elizabeth, Bielefeldt-Ohmann, Helle, Johnston, Matthew S, Kendall, Lon V, Izzo, Angelo A
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024781/
https://ncbi.nlm.nih.gov/pubmed/31952557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-CM-19-000047
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