Sodium Iodide Symporter (NIS)-Mediated Radionuclide ((131)I, (188)Re) Therapy of Liver Cancer After Transcriptionally Targeted Intratumoral in Vivo NIS Gene Delivery

We reported the therapeutic efficacy of (131)I in hepatocellular carcinoma (HCC) cells stably expressing the sodium iodide symporter (NIS) under the control of the tumor-specific α-fetoprotein (AFP) promoter. In the current study we investigated the efficacy of adenovirus-mediated in vivo NIS gene t...

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Autors principals: Klutz, Kathrin, Willhauck, Michael J., Wunderlich, Nathalie, Zach, Christian, Anton, Martina, Senekowitsch-Schmidtke, Reingard, Göke, Burkhard, Spitzweg, Christine
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225037/
https://ncbi.nlm.nih.gov/pubmed/21488714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.158
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