Sodium Iodide Symporter (NIS)-Mediated Radionuclide ((131)I, (188)Re) Therapy of Liver Cancer After Transcriptionally Targeted Intratumoral in Vivo NIS Gene Delivery

We reported the therapeutic efficacy of (131)I in hepatocellular carcinoma (HCC) cells stably expressing the sodium iodide symporter (NIS) under the control of the tumor-specific α-fetoprotein (AFP) promoter. In the current study we investigated the efficacy of adenovirus-mediated in vivo NIS gene t...

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Detalhes bibliográficos
Main Authors: Klutz, Kathrin, Willhauck, Michael J., Wunderlich, Nathalie, Zach, Christian, Anton, Martina, Senekowitsch-Schmidtke, Reingard, Göke, Burkhard, Spitzweg, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225037/
https://ncbi.nlm.nih.gov/pubmed/21488714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.158
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