EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene

We recently demonstrated tumor-selective iodide uptake and therapeutic efficacy of combined radiovirotherapy after systemic delivery of the theranostic sodium iodide symporter (NIS) gene using a dendrimer-coated adenovirus. To further improve shielding and targeting we physically coated replication-...

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Detalhes bibliográficos
Main Authors: Grünwald, Geoffrey K, Vetter, Alexandra, Klutz, Kathrin, Willhauck, Michael J, Schwenk, Nathalie, Senekowitsch-Schmidtke, Reingard, Schwaiger, Markus, Zach, Christian, Wagner, Ernst, Göke, Burkhard, Holm, Per S, Ogris, Manfred, Spitzweg, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889187/
https://ncbi.nlm.nih.gov/pubmed/24193032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.58
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