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Inhibitory role of TACE/ADAM17 cytotail in protein ectodomain shedding
AIM: To determine if the cytotail of the principal sheddase tumor necrosis factor-α converting enzyme (TACE; ADAM17) controls protein ectodomain shedding. METHODS: Site-directed mutagenesis was performed to derive TACE variants. The resulting TACE expression plasmids with amino acid substitutions in...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Baishideng Publishing Group Co., Limited
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224872/ https://ncbi.nlm.nih.gov/pubmed/22125668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v2.i11.246 |
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