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Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

BACKGROUND: The correlation between neurofibrillary tangles of tau and disease progression in the brains of Alzheimer's disease (AD) patients remains an area of contention. Innovative data are emerging from biochemical, cell-based and transgenic mouse studies that suggest that tau oligomers, a...

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Autores principales: Lasagna-Reeves, Cristian A, Castillo-Carranza, Diana L, Sengupta, Urmi, Clos, Audra L, Jackson, George R, Kayed, Rakez
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224595/
https://ncbi.nlm.nih.gov/pubmed/21645391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-39
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