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Biotinylation is a natural, albeit rare, modification of human histones

Previous studies suggest that histones H3 and H4 are posttranslationally modified by binding of the vitamin biotin, catalyzed by holocarboxylase synthetase (HCS). Albeit a rare epigenetic mark, biotinylated histones were repeatedly shown to be enriched in repeat regions and repressed loci, participa...

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Main Authors: Kuroishi, Toshinobu, Rios-Avila, Luisa, Pestinger, Valerie, Wijeratne, Subhashinee S. K., Zempleni, Janos
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224183/
https://ncbi.nlm.nih.gov/pubmed/21930408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.08.030
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