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Repression of Transposable Elements by Histone Biotinylation
Transposable elements constitute >40% of the human genome; transposition of these elements increases genome instability and cancer risk. Epigenetic mechanisms are important for transcriptional repression of retrotransposons, thereby preventing transposition events. Binding of biotin to histones,...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Nutrition
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777482/ https://ncbi.nlm.nih.gov/pubmed/19812216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.109.111856 |
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