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Biotinylation is a natural, albeit rare, modification of human histones
Previous studies suggest that histones H3 and H4 are posttranslationally modified by binding of the vitamin biotin, catalyzed by holocarboxylase synthetase (HCS). Albeit a rare epigenetic mark, biotinylated histones were repeatedly shown to be enriched in repeat regions and repressed loci, participa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224183/ https://ncbi.nlm.nih.gov/pubmed/21930408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.08.030 |
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