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K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts
Covalent modifications of histones play a role in regulating telomere attrition and cellular senescence. Biotinylation of lysine (K) residues in histones, mediated by holocarboxylase synthetase (HCS), is a novel diet-dependent mechanism to regulate chromatin structure and gene expression. We have pr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854078/ https://ncbi.nlm.nih.gov/pubmed/19369050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2009.01.010 |
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