Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β

The airway is a primary portal of entry for noxious environmental stimuli that can trigger airway remodeling, which contributes significantly to airway obstruction in chronic obstructive pulmonary disease (COPD) and chronic asthma. Important pathologic components of airway remodeling include fibrosi...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kitamura, Hideya, Cambier, Stephanie, Somanath, Sangeeta, Barker, Tyren, Minagawa, Shunsuke, Markovics, Jennifer, Goodsell, Amanda, Publicover, Jean, Reichardt, Louis, Jablons, David, Wolters, Paul, Hill, Arthur, Marks, James D., Lou, Jianlong, Pittet, Jean-Francois, Gauldie, Jack, Baron, Jody Lynn, Nishimura, Stephen L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2011
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223836/
https://ncbi.nlm.nih.gov/pubmed/21646718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45589
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