Transcription of the Transforming Growth Factor β Activating Integrin β8 Subunit Is Regulated by SP3, AP-1, and the p38 Pathway

Integrin αvβ8 is a critical regulator of transforming growth factor β activation in vasculogenesis during development, immune regulation, and endothelial/epithelial-mesenchymal homeostasis. Recent studies have suggested roles for integrin β8 in the pathogenesis of chronic obstructive pulmonary disea...

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Hlavní autoři: Markovics, Jennifer A., Araya, Jun, Cambier, Stephanie, Jablons, David, Hill, Arthur, Wolters, Paul J., Nishimura, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915706/
https://ncbi.nlm.nih.gov/pubmed/20519498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113977
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