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Transcription of the Transforming Growth Factor β Activating Integrin β8 Subunit Is Regulated by SP3, AP-1, and the p38 Pathway
Integrin αvβ8 is a critical regulator of transforming growth factor β activation in vasculogenesis during development, immune regulation, and endothelial/epithelial-mesenchymal homeostasis. Recent studies have suggested roles for integrin β8 in the pathogenesis of chronic obstructive pulmonary disea...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915706/ https://ncbi.nlm.nih.gov/pubmed/20519498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113977 |
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