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Integrin αvβ8-Mediated Activation of Transforming Growth Factor-β Inhibits Human Airway Epithelial Proliferation in Intact Bronchial Tissue

Transforming growth factor (TGF)-β is a potent multifunctional cytokine that is an essential regulator of epithelial proliferation. Because TGF-β is expressed almost entirely in a latent state in vivo, a major source of regulation of TGF-β function is its activation. A subset of integrins, αvβ8 and...

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書誌詳細
主要な著者: Fjellbirkeland, Lars, Cambier, Stephanie, Broaddus, V. Courtney, Hill, Arthur, Brunetta, Paul, Dolganov, Gregory, Jablons, David, Nishimura, Stephen L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2003
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868219/
https://ncbi.nlm.nih.gov/pubmed/12875973
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