Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease

Airway remodeling, caused by inflammation and fibrosis, is a major component of chronic obstructive pulmonary disease (COPD) and currently has no effective treatment. Transforming growth factor–β (TGF-β) has been widely implicated in the pathogenesis of airway remodeling in COPD. TGF-β is expressed...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Transl Med
मुख्य लेखकों: Minagawa, Shunsuke, Lou, Jianlong, Seed, Robert I., Cormier, Anthony, Wu, Shenping, Cheng, Yifan, Murray, Lynne, Tsui, Ping, Connor, Jane, Herbst, Ronald, Govaerts, Cedric, Barker, Tyren, Cambier, Stephanie, Yanagisawa, Haruhiko, Goodsell, Amanda, Hashimoto, Mitsuo, Brand, Oliver J., Cheng, Ran, Ma, Royce, McKnelly, Kate J., Wen, Weihua, Hill, Arthur, Jablons, David, Wolters, Paul, Kitamura, Hideya, Araya, Jun, Barczak, Andrea J., Erle, David J., Reichardt, Louis F., Marks, James D., Baron, Jody L., Nishimura, Stephen L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341974/
https://ncbi.nlm.nih.gov/pubmed/24944194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008074
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