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Involvement of Histone Acetylation of Sox17 and Foxa2 Promoters during Mouse Definitive Endoderm Differentiation Revealed by MicroRNA Profiling

Generation of hepatocyte from embryonic stem cells (ESCs) holds great promise for hepatocyte replacement therapy to treat liver diseases. Achieving high efficiency of directed differentiation of ESCs to hepatocyte is of critical importance. Previously, Wnt3a has been reported to promote Activin A-in...

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Autors principals: Fu, Shijun, Fei, Qi, Jiang, Hua, Chuai, Shannon, Shi, Song, Xiong, Wen, Jiang, Lei, Lu, Chris, Atadja, Peter, Li, En, Shou, Jianyong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223193/
https://ncbi.nlm.nih.gov/pubmed/22132182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027965
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