Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts

Achieving effective treatment outcomes for patients with glioblastoma (GBM) has been impeded by many obstacles, including the pharmacokinetic limitations of antitumor agents, such as topotecan (TPT). Here, we demonstrate that intravenous administration of a novel nanoliposomal formulation of TPT (nL...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Serwer, Laura P., Noble, Charles O., Michaud, Karine, Drummond, Daryl C., Kirpotin, Dmitri B., Ozawa, Tomoko, Prados, Michael D., Park, John W., James, C. David
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2011
Θέματα:
Basic and Translational Investigations
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223095/
https://ncbi.nlm.nih.gov/pubmed/21954443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor139
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