Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model

Treatment of malignant gliomas represents one of the most formidable challenges in oncology. The combination of surgery, radiation, and chemotherapy yields median survivals of less than one year. Here we demonstrate the use of a minimally invasive surgical technique, convection-enhanced delivery (CE...

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Detalhes bibliográficos
Main Authors: Saito, Ryuta, Krauze, Michal T., Noble, Charles O., Drummond, Daryl C., Kirpotin, Dmitri B., Berger, Mitchel S., Park, John W., Bankiewicz, Krystof S.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2006
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871954/
https://ncbi.nlm.nih.gov/pubmed/16723630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-001
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