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Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts

BACKGROUND: Liposomal drug packaging is well established as an effective means for increasing drug half-life, sustaining drug activity, and increasing drug efficacy, whether administered locally or distally to the site of disease. However, information regarding the relative effectiveness of peripher...

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Detalhes bibliográficos
Main Authors: Chen, Pin-Yuan, Ozawa, Tomoko, Drummond, Daryl C., Kalra, Ashish, Fitzgerald, Jonathan B., Kirpotin, Dmitri B., Wei, Kuo-Chen, Butowski, Nicholas, Prados, Michael D., Berger, Mitchel S., Forsayeth, John R., Bankiewicz, Krystof, James, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548589/
https://ncbi.nlm.nih.gov/pubmed/23262509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos305
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