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Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

Inner ear hair cells convert the mechanical stimuli of sound, gravity, and head movement into electrical signals. This mechanotransduction process is initiated by opening of cation channels near the tips of hair cell stereocilia. Since the identity of these ion channels is unknown, and mutations in...

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Hlavní autoři: Kawashima, Yoshiyuki, Géléoc, Gwenaëlle S.G., Kurima, Kiyoto, Labay, Valentina, Lelli, Andrea, Asai, Yukako, Makishima, Tomoko, Wu, Doris K., Della Santina, Charles C., Holt, Jeffrey R., Griffith, Andrew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223072/
https://ncbi.nlm.nih.gov/pubmed/22105175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60405
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