Engagement of Descending Inhibition from the Rostral Ventromedial Medulla Protects Against Chronic Neuropathic Pain

A puzzling observation is why peripheral nerve injury results in chronic pain in some, but not all, patients. We explored potential mechanisms that may prevent the expression of chronic pain. Sprague-Dawley (SD) or Holtzman (HZ) rats showed no differences in baseline sensory thresholds or responses...

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Hauptverfasser: De Felice, Milena, Sanoja, Raul, Wang, Ruizhong, Vera-Portocarrero, Louis, Oyarzo, Janice, King, Tamara, Ossipov, Michael H., Vanderah, Todd W., Lai, Josephine, Dussor, Gregory O., Fields, Howard L., Price, Theodore J., Porreca, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222148/
https://ncbi.nlm.nih.gov/pubmed/21745713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.06.008
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