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TCF-1 Regulates Thymocyte Survival via a RORγt-dependent Pathway
Survival of CD4(+)CD8(+) double positive (DP) thymocytes plays a critical role in shaping the peripheral T cell repertoire. However, the mechanisms responsible for the regulation of DP thymocyte lifespan remain poorly understood. In this work, we demonstrate that TCF-1 regulates DP thymocyte surviva...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221934/ https://ncbi.nlm.nih.gov/pubmed/22039299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101205 |
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