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Transcription factor network regulating CD4(+)CD8(+) thymocyte survival
More than 80% of thymocytes are CD4(+)CD8(+) double positive (DP) cells which subject to positive/negative selection. The lifespan of DP thymocytes is critical in shaping the peripheral T cell repertoire essential for mounting immune responses against foreign, but not self, antigens. During T cell m...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281554/ https://ncbi.nlm.nih.gov/pubmed/22321106 |
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