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Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria
Signaling by innate immune receptors initiates and orchestrates the overall immune responses to infection. Macrophage receptors recognizing pathogens can be broadly grouped into surface receptors and receptors restricted to intracellular compartments, such as phagosomes and the cytoplasm. There is a...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221871/ https://ncbi.nlm.nih.gov/pubmed/22031762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100232 |
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