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TB, or not TB: that is the question – does TLR signaling hold the answer?

Innate immunity critically depends on signaling by Toll-like receptors (TLRs) that rely heavily on an intracellular adapter protein called myeloid differentiation factor 88 (MyD88). Adaptive immune defenses are generally thought to be orchestrated by innate immune responses and so should require int...

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Bibliographic Details
Main Authors: Doherty, Terence M., Arditi, Moshe
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC535076/
https://ncbi.nlm.nih.gov/pubmed/15599394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423867
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