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TB, or not TB: that is the question – does TLR signaling hold the answer?

Innate immunity critically depends on signaling by Toll-like receptors (TLRs) that rely heavily on an intracellular adapter protein called myeloid differentiation factor 88 (MyD88). Adaptive immune defenses are generally thought to be orchestrated by innate immune responses and so should require int...

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Главные авторы: Doherty, Terence M., Arditi, Moshe
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC535076/
https://ncbi.nlm.nih.gov/pubmed/15599394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423867
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