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Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria

Signaling by innate immune receptors initiates and orchestrates the overall immune responses to infection. Macrophage receptors recognizing pathogens can be broadly grouped into surface receptors and receptors restricted to intracellular compartments, such as phagosomes and the cytoplasm. There is a...

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Bibliografische gegevens
Hoofdauteurs: Wolf, Andrea J., Arruda, Andrea, Reyes, Christopher N., Kaplan, Amber T., Shimada, Takahiro, Shimada, Kenichi, Arditi, Moshe, Liu, George, Underhill, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221871/
https://ncbi.nlm.nih.gov/pubmed/22031762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100232
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