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Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria

Signaling by innate immune receptors initiates and orchestrates the overall immune responses to infection. Macrophage receptors recognizing pathogens can be broadly grouped into surface receptors and receptors restricted to intracellular compartments, such as phagosomes and the cytoplasm. There is a...

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Detalhes bibliográficos
Main Authors: Wolf, Andrea J., Arruda, Andrea, Reyes, Christopher N., Kaplan, Amber T., Shimada, Takahiro, Shimada, Kenichi, Arditi, Moshe, Liu, George, Underhill, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221871/
https://ncbi.nlm.nih.gov/pubmed/22031762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100232
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